from
£9.79
Sumatriptan is a migraine treatment, alleviating associated symptoms. It works by narrowing blood vessels in the head, preventing pain signals from being sent to the brain. Sumatriptan 50mg & 100mg are available to buy online from Chemist Click.
You can buy sumatriptan online from our UK registered pharmacy. You will be required to answer a few questions about your health, to ensure that treatment is suitable for you.
Name & Dosage | x6 Tablets | x12 Tablets | x18 Tablets |
---|---|---|---|
Sumatriptan 50mg Tablets | £9.79 | £15.49 | £23.29 |
Sumatriptan 100mg Tablets | £10.89 | £19.75 | £29.49 |
Type of medicine | Selective Serotonin Receptor Agonists |
---|---|
Mechanism of action | Reduces pain signals in the brain |
Active ingredient | Sumatriptan succinate |
Strength | 50mg; 100mg |
Effective within | 30 - 60 minutes |
Dosage Instructions | Take ONE tablet at the onset of migraine |
Manufacturer | Accord Healthcare, Mylan, Dr Reddy’s, Aurobindo Pharma - Milpharm, Dexcel Pharma, Bristol Labs, Almus, Teva |
Use with alcohol | In moderation |
Sumatriptan is a migraine and cluster headache treatment. It offers migraine relief and helps to alleviate symptoms such as pain, nausea, and sensitivity to light and sound.
Sumatriptan tablets work by acting on serotonin (5HT) receptors in the brain, causing the blood vessels to narrow. This prevents signals from being sent, stopping migraines.
Sumatriptan has also been shown to decrease the activity of the trigeminal nerve, which is responsible for carrying pain pulses from your head to your central nervous system.
Sumatriptan tablets usually take around 30-60 minutes to work. Sumatriptan nasal spray is faster acting, taking around 15 minutes to work.
There are several triptans available. Triptan is the class of drug sumatriptan belongs to, used for the acute treatment of migraines.
These migraine treatments work in a similar way to relieve migraine symptoms; however, they offer slightly different side effects, duration and dosage. Sumatriptan alternatives include:
You should not use sumatriptan tablets to try to prevent an attack – only use it after your migraine symptoms start.
There are things you can do to try and prevent a migraine:
The recommended starting dosage for sumatriptan is 50mg and you can take another tablet after 2 hours if the migraine returns.
Sumatriptan 100mg is only used when sumatriptan 50mg tablets have provided limited relief.
The maximum dosage of sumatriptan is 300mg within a 24 hour period. You should not take more than this. An overdose can result in feeling weak or fainting, reduced heart rate, feeling sick, loss of bowel and bladder control, and fatigue.
In more serious cases, taking too much sumatriptan can narrow blood vessels to a degree which causes heart problems including chest pain, an abnormal heart rhythm, and even a heart attack.
Like all medication, there may be side effects with sumatriptan. Not everyone will experience them.
Common side effects of sumatriptan tablets include:
It is unlikely that healthy adults will experience any long-term side effects from sumatriptan.
If you experience any of the following symptoms, you should call 999 or seek urgent medical attention:
You should read the patient information leaflet for a full list of side effects.
Sumatriptan side effects vary depending on the individual circumstances and not everyone experiences them. For those who do, dizziness, chest pain and drowsiness usually resolve within a few hours. Other side effects such as nausea, tingling, flushing and fatigue typically stop within a few hours to days after taking the medication. You should seek urgent medical advice if you experience prolonged or severe symptoms, as these could indicate a serious reaction.
You should avoid taking sumatriptan if you have:
You should let your doctor or pharmacist know if you have certain risk factors or fall into the high-risk category, which include:
They can determine whether it is safe for you to take sumatriptan by assessing whether the benefits outweigh the risks involved. This is because sumatriptan can affect your heart, and certain conditions can increase the chances of complications.
There are certain drugs that you cannot take with sumatriptan tablets, due to possible interactions; for example:
You should always let your doctor or pharmacist know if you are taking other medication, herbal products or dietary supplements so that they can check for interactions with sumatriptan tablets.
There are no listed interactions between sumatriptan and ibuprofen, and they are safe to take together.
There is no listed interaction between sumatriptan and paracetamol, and they are safe to take together.
Taking sumatriptan tablets together with sertraline, increases the chances of a rare but serious side effect, known as serotonin syndrome.
There is a risk of serotonin syndrome when sumatriptan is taken together with amitriptyline.
There is no listed interaction in the BNF between sumatriptan and propranolol. Used as a preventative therapy for migraines, propranolol is thought to slow the rate at which sumatriptan leaves the body, which can increase the risk of side effects. Your doctor or pharmacist will be able to inform you whether you can take the two together.
Whilst alcohol does not have a direct impact on sumatriptan, you should avoid alcohol if you are experiencing a migraine. It can exacerbate symptoms of a migraine attack.
Although not thought to be harmful, there is not enough information about the safety profile of taking sumatriptan while pregnant. If you are pregnant and wish to take sumatriptan, you should speak to your doctor.
Sumatriptan is present in breastmilk, but the amount is thought to be too small to be harmful. You should speak to your doctor or pharmacist if you wish to take sumatriptan tablets whilst breastfeeding. If it is safe to do so, you should stop breastfeeding for 12 hours after taking a tablet.
The general rule of thumb is that if you are using sumatriptan pills more than 2 times a week, this is too much, and you may be at risk of a medicines overuse headache.
Whilst sumatriptan is not addictive, it should not be used daily. If you need to use sumatriptan daily, you should see your doctor.
You can buy sumatriptan over the counter in most UK pharmacies – the dose is limited to 50mg and limited to 2 tablets per pack.
You will need to visit your GP if you wish to use sumatriptan injections.
Yes, there are no listed interactions between sumatriptan and paracetamol or sumatriptan and ibuprofen.
You should avoid alcohol if you are experiencing a migraine. It can exacerbate symptoms of a migraine attack.
product rated 4.9/5
These tablets work very quickly when taken at initial onset of my cluster migraine. I find if I leave and take when full migraine they take longer.
By Vicky (via TrustPilot)When ever I have a horrid migraine start take one of these 50mg little miracles and starts to work with in 20-30 mins… highly recommend Sumatriptans as they actually work and are cheaper than the other brands 👍🏼
By Kitty (via TrustPilot)I have suffered with migraines on and off for years which I used to take regular medication for. They have recently increased again due to peri menopause. These sumatriptan tablets prevent me having to take bucket loads of pain killers when a migraine strikes and keeps the nausea at a distance. Highly recommended.
By Lisa Goulding (via TrustPilot)Helps with my occasional migraines. Wish I'd discovered them earlier. I usually take one the moment I suspect it coming. Sometimes I pair with ibuprofen , but it's usually very effective!
By Daniela Nicula (via TrustPilot)Superintendent Pharmacist
Written by Chemist Click
First created 3rd February 2025
Last reviewed 10th October 2025
Our team of experienced pharmacists and healthcare professionals are dedicated to providing the highest level of care and service to every customer, ensuring that they receive the best possible healthcare experience.
Constantly good service, always very quick to deliver items.
By Phil ElliottHighly recommend. Fast delivery. Reliable.
By Carlene GraceHave ordered before and had a great experience. I order a hayfever spray that my GP no longer issues on prescription. Easy process. Will definitely use again.
By CarolineHad a great experience, right from consultation to medicine delivery it was very efficient and professional. Thanks.
By Shefali PathakEasy to navigate website, regularly use their service, prompt timely delivery, discounts for regular customers could be considered.
By ArunI shopped around before purchasing and items price was good. Delivery was prompt and P+P reasonable. Item was as described. Good service.
By Mark LockettGood website, intuitive with great information. Efficient, from payment through to delivery, and good communication updates all the way.
By Graeme WalkerExcellent service. I ordered some medication which was dispatched very quickly and arrived super fast. The medication has a very long expiry date. I would definitely order again. Many thanks.
By Ian TBest company there is for me. Great service and excellent quality plus pricing is perfect. I wouldn't want to use anyone else in all honesty. I have recommended this company to all my friends. It's a tricky subject for us older guys but this company makes it all respectful and they discretion is very much appreciated by us all.
By Neil Franklin