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Treclin Gel 1x Tube/x2 Tubes/x3 Tubes
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£29.99
Treclin is an acne treatment that works to clear breakouts, blackheads, whiteheads, blemishes and clogged pores. Treclin contains clindamycin (an antibiotic that reduces the growth of bacteria) and tretinoin (which helps to regulate the turnover of skin cells, making it harder for acne to develop).
Treclin Gel 1x Tube/x2 Tubes/x3 Tubes
Buy Treclin gel online
Buy treclin gel from our UK-registered pharmacy. Treclin 1 /0.025 w/w gel is a prescription medicine which can be purchased online. Once you have completed our quick and easy consultation process, our in-house pharmacist will issue your prescription.
Treclin Gel Prices
| Name & Dosage | x1 Tube (30g) |
x2 Tube (30g) |
x3 Tube (30g) |
|---|---|---|---|
| Treclin Gel Tube (30g) |
£29.99 | £53.99 | £74.99 |
Summary for Treclin Gel
| Medication Class | Topical antibiotics and retinoids |
|---|---|
| Mechanism of action | Reduces infection and inflammation, increases cell turnover |
| Active ingredient | Clindamycin / Tretinoin |
| Strength | 1% / 0.025% |
| Effective within | 6 weeks |
| Dosage Instructions | Daily |
| Manufacturer | Meda Pharmaceuticals |
About Treclin gel
Key Points
- Effectively treats acne vulgaris
- Combines the effects of both a retinoid and antibiotic
- Suitable for moderate acne
- Prevents new blackheads and whiteheads, sheds dead skin cells
What is Treclin?
Treclin is a topical acne treatment that contains an antibiotic, clindamycin and a retinoid called tretinoin. It works to reduce the symptoms of acne. It is usually used when over the counter treatments and non-antibiotic prescription medication have failed.
What is Treclin Gel used for?
It is used to treat and prevent the formation of early acne lesions such as blackheads and whiteheads.
What does Treclin Gel do?
Treclin gel prevents the growth of bacteria that causes acne. It also reduces the amount of oil your skin produces sebum production, allowing the skin to shed and reduce inflammation associated with acne.
Important note: You will not get better results or see faster results by using more than the recommended amount of Treclin. It can cause skin irritation and increase the likelihood of experiencing side effects.
Please note: Exposure to natural or artificial light should be avoided when using this medicine because your skin may be more sensitive to sunburn and other adverse effects of the sun. It is important to use a broad-spectrum SPF of at least 30 and wear protective clothing when you are outside. If your face becomes sunburnt, immediately stop using Treclin until it is healed.
Treclin gel alternative
Treclin vs Epiduo
Both Treclin and Epiduo contain derivatives of vitamin A at different concentrations depending on the severity of acne and combined with two different antibiotics. Treclin, combined with clindamycin, contains 0.025% tretinoin and is used for moderate case acne, while Epiduo, combined with benzyl peroxide, contains 1% adapalene (retinoid) and is used for mild to moderate acne.
Treclin vs differin
Treclin has a combination of both an antibiotic and a retinoid, targeting bacterial infection and promoting cell turnover, while Differin contains adapalene, a retinoid which modulates skin cell turnover and reduces inflammation. Treclin Gel may be better suited for those with acne that has a significant bacterial component, due to the presence of clindamycin antibiotic. Differin gel is typically used to treat mild moderate acne because it does not contain any antibiotics.
Treclin ingredients
Active ingredient: clindamycin and tretinoin
Inactive ingredients: purified water, glycerol, carbomers, methyl parahydroxybenzoate (E 218), polysorbate 80, disodium edetate, anhydrous citric acid, propyl parahydroxybenzoate (E 216), butyl hydroxytoluene (E321), trometamol.
How to Use Treclin Gel
Wash your face with lukewarm water and mild cleanser then dry. Apply Treclin 20 minutes after the skin has completely dried.
Spread a pea-sized amount evenly on the face at bedtime. Do not use more than suggested, as this will not provide faster or better results and may cause irritation and discomfort to the skin.
Use this medication at bedtime and avoid sun light and artificial light because the skin is prone to reacting when using Treclin. A sunscreen with a minimum SPF of 30 can be used to avoid irritation.
Avoid contact with the lips and eyes, or any area on the face that is wounded, such as sunburnt areas, or areas affected by eczema. If Treclin comes into contact with your eyes, rinse with water.
Treclin Gel Dosage Instructions
How to use treclin gel
To use Treclin, apply a pea-sized amount on your fingertip, dabbing the gel on sections where acne is present. Gently rub the gel into your skin, spreading it evenly across your face.
Before you use Treclin, wash your face with warm water and a gentle facewash. Ensure that your face is dry before applying the gel.
When should I use Treclin?
You should use Treclin gel at night. This is because it contains a retinoid, which can increase the skin’s sensitivity to sunlight. You should use Treclin every night until your course is complete.
Treclin Gel Side Effects
Common side effects of Treclin include but are not limited to:
- Dryness and redness of the skin
- Burning sensation
- Increased sensitivity to sun light, sunburn
- Increased sebum production
- Skin rash and scaling
Uncommon or rare side effects:
- Hypersensitivity
- Acne
- Headache
- Eye irritation
- Underactive thyroid gland
- Gastroenteritis
- Feeling hot and pain
We advise checking the full list of side effects here. You may also wish to visit the acne section on the NHS website for more useful information.
If you experience any of the above side effects, or ones not included in the list, contact your doctor or pharmacist immediately. In the case of a medical emergency, call 999 or visit your local hospital’s A&E department.
You can also report side effects directly via the MHRA’s Yellow Card Scheme. Reporting side effects can help provide more information on the safety of this medicine.
Treclin Gel Warnings
Do not use Treclin if:
- You are pregnant
- You are planning to become pregnant
- You are allergic to clindamycin, tretinoin, lincomycin or any of the other ingredients of this medication
- You are suffering from acne that is characterised by pustular and deep cystic nodular acne lesions (acne conglobata and acne fulminans).
- You are suffering from acute eczema which is characterised by inflamed, red, dry and scaly skin
- You are suffering from rosacea, a skin disease which affects the face and is characterised by redness, pimples and peeling.
- You are suffering from other acute inflammatory conditions of the skin (e.g. folliculitis), especially around the mouth (perioral dermatitis)
- You have a chronic inflammatory bowel disease (e.g. Crohn’s disease or ulcerative colitis)
- You have a history of colitis with past antibiotic use which is characterised by prolonged or significant diarrhoea or abdominal cramps
- If you or a member of your family have ever suffered from skin cancer
You should speak to your doctor if you wish to use Treclin and have:
- Atopic eczema or other skin conditions
- Severe acne
- Recently used antibiotics
What should I do if Treclin has not worked?
If Treclin has not been successful, you should visit your doctor or pharmacist. You may be prescribed with an alternative antibiotic, such as Zineryt. For females, it is common practice to be prescribed with the contraceptive pill, as this can help to reduce acne caused by hormonal changes in the body.
Treclin Gel Interactions
The effectiveness of some medicines can be altered by Treclin. Inform your GP or pharmacist if you are taking or have recently taken or might take any other medicines including medicines that you buy without a prescription or herbal medicines.
If you are using products that contain any of the following, wait until the effects have subsided before using Treclin Gel:
- Sulphur
- Salicylic acid
- Benzoyl peroxide
- Resorcinol
- Any chemical abrasives
You should also avoid using facial products which have a drying effect such as:
- Abrasive soaps
- Alcohol
- Astringents
- Spices or lime
Seek advice from your GP or pharmacist before using this medicine together with other medicinal products containing:
- Erythromycin or Metronidazole
- Aminoglycosides
- Other antibiotics or corticosteroids
- Neuromuscular blocking medicines e.g muscle relaxants used in anaesthesia
- Warfarin or similar medicines used to thin the blood (your doctor may need to take regular blood tests to check how well your blood can clot).
Treclin Gel and Pregnancy/Breastfeeding
Do not use Treclin if you are pregnant or planning to become pregnant. If you are of childrearing age, you should use contraception while using Treclin and for one month after you stop using this medication. Do not continue using treclin and contact your doctor immediately if you have prolonged or significant diarrhoea or abdominal cramps.
It is unknown if Treclin can pass through human milk, so you should not use it when breastfeeding.
Frequently Asked Questions
Treclin can make skin appear worse within the first 7-10 days. This is known as the treclin gel purge. You should start to see that Treclin is working after 2-3 weeks, and by week 6, you should notice that Treclin is clearing your acne. You should not use Treclin for more than 12 weeks unless your doctor or pharmacist advises you to do so.
If you feel that Treclin is not helping your skin, you should see your doctor or pharmacist.
You can use Treclin gel for up to 12 weeks. It is important to continue to use Treclin for up to 12 weeks and you should not exceed the length of treatment that your doctor or pharmacist prescribes. This is because it can cause your skin to become resistant to the antibiotic clindamycin, which is contained in Treclin.
Important note: Using Treclin beyond 12 weeks may contribute to antibiotic resistance. You should only use Treclin again after a lengthy break, to avoid your skin becoming resistant to Treclin.
The purge is when your skin experiences dryness, peeling and small spots. Essentially, it is your skin that gets worse before it gets better. Purging happens because Treclin contains a retinoid, which increases the rate at which your body produces new skin. It is causing the top layer of your skin to shed and get rid of the bacteria, sebum and dead skin cells. This term is often referred to as the “tretinoin purge” or “skin purging”.
The tretinoin purge can last for around 2-6 weeks before your skin clears up. Not everyone experiences purging, but it is common when using retinoids.
Important note: Skin purging looks like small red bumps and irritation on your skin, but it is a good sign that treatment is working. If you experience rashes, raised skin, or your skin is breaking, it may be reacting. You should stop treatment and visit your doctor or pharmacist for advice.
Once your course of Treclin is complete, your prescriber will inform you whether you should continue to use Treclin. This will depend on your response to treatment and the length of time you have been using Treclin for. If your acne has cleared, you may be prescribed with Differin or Epiduo, as these products also contain a retinoid. They do not contain antibiotics and are therefore safe to use long term to prevent outbreaks and maintain your skin.
Treclin contains a retinoid that is proven to help reduce wrinkles and treat rosacea, hyperpigmentation, and acne scars. However, it is not licensed to treat these conditions and you should visit your dermatologist if you wish to seek treatment for these conditions.
Treclin contains 0.025% tretinoin in combination with 1% clindamycin, an antibiotic.
You should not use Treclin with other acne treatments unless your doctor or pharmacist instructs you to. This is because most acne treatments tend to dry and irritate the skin.
Important note: Do not use Treclin with any other antibiotics as this can contribute to antibiotic resistance. You should not use Treclin if you have used an alternative treatment such as Duac, which contains the same antibiotic.
Product Reviews
product rated 4.8/5
Only one week in but no bad reaction and acne seems to have calmed down already.
By Clare (via TrustPilot)
Great product, really helping
By Mary Valentine (via TrustPilot)
Ideal combination drug for me ( tretin A and antibiotics )
By Janos Bakos (via TrustPilot)
Excellent product for moderate acne
By Rosalind Haywood (via TrustPilot)
Superintendent Pharmacist
Written by Chemist Click
First created 22nd April 2025
Last reviewed 9th October 2025
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