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Buy Tadalafil Online in the UK

You can buy tadalafil online today from Chemist Click, for a fast and discreet delivery to your door. To receive treatment, complete a free consultation above, for our UK-based team to review.

Tadalafil Prices

Name & Dosage x4 Tablets x8 Tablets x12 Tablets x16 Tablets x24 Tablets x28 Tablets x32 Tablets x56 Tablets x64 Tablets x84 Tablets x168 Tablets
Tadalafil 2.5mg Tablets £19.45 £36.89 £45.89
Tadalafil 5mg Tablets £18.45 £35.95 £47.91 £99.95
Tadalafil 10mg Tablets £8.89 £14.89 £19.89 £25.49 £34.89 £43.99 £79.89
Tadalafil 20mg Tablets £9.79 £16.89 £23.79 £28.49 £39.89 £49.89 £89.89

Summary for Tadalafil Tablets

Medication Class PDE5 inhibitor
Mechanism of Action Increases blood flow to the penis, helping to achieve and maintain an erection
Active ingredient Tadalafil
Strengths 2.5mg & 5mg (daily dose); 10mg & 20mg (when required dose)
Effective within 2.5mg & 5mg have a continuous effect; 10mg & 20mg effective within 30 mins
Dosage Instructions 2.5mg & 5mg – Take one dose daily continuously; 10mg & 20mg – Take one dose 30 minutes before sexual activity
Manufacturer Teva, Mylan, Accord, Milpharm
Use with alcohol In moderation

What is Tadalafil?

Tadalafil is a generic medicine used to treat erectile dysfunction. It contains the same active ingredient as Cialis but is available as a non-branded version, often referred to as “generic Cialis.”

Tadalafil comes in two different variations:

  • Tadalafil 2.5mg & 5mg – Known as Tadalafil once daily tablets
  • Tadalafil 10mg & 20mg – Known as Tadalafil 36-hour

 

Overview of Tadalafil Strengths, Onset and Duration of Action

Strength Typical Use How long to start working* How long it lasts
2.5 mg Daily (once every day) Builds over 2-3 days (some benefit after first few doses) Continuous coverage with daily dosing
5 mg Daily (once every day) Builds over 2-3 days (steady effect after a few days) Continuous coverage with daily dosing
10 mg On-demand (when needed) 30-60 minutes before sex (some respond from ~30 min) Up to 36 hours
20 mg On-demand (when needed) 30-60 minutes before sex (some respond from ~30 min) Up to 36 hours

*Actual onset and duration may vary between individuals and depend on medical factors

 

How Does Tadalafil Work?

Tadalafil works by encouraging blood flow to the penis during sexual stimulation. This helps users to achieve and maintain an erection.

Important note: Tadalafil will only work where there is sexual stimulation. It will not help to increase sexual desire.

Tadalafil Ingredients

Active ingredient: Tadalafil

Inactive ingredients: Croscarmellose sodium, lactose monohydrate, sodium lauryl sulfate, hydroxypropyl cellulose, magnesium stearate, microcrystalline.

*Whilst the active ingredient will remain the same, the inactive ingredients may differ amongst brands. You should read the Tadalafil patient information leaflet supplied with your medication, for a full list of ingredients.

Tadalafil Dosage Instructions

Which Tadalafil Dose Should I Choose?

Choosing the right Tadalafil dosage depends on how often you plan to have sex, how quickly you want the treatment to work, and how your body responds to the medicine.

Tadalafil 2.5mg or 5mg tablets (daily use)

If you prefer spontaneity or want to avoid planning around sexual activity, a once-daily low dose is usually the best option.

Instructions: Take one tablet daily

2.5mg: The lowest strength, ideal for men who are sensitive to side effects or want a gentler introduction to treatment. It builds up gradually in your system and offers continuous coverage after a few days.

5mg: The most commonly prescribed daily dose. It’s strong enough to provide reliable results while still being suitable for long-term use. Many men also find it helps with urinary symptoms caused by benign prostatic hyperplasia (BPH).

Best for: regular sexual activity, couples who prefer spontaneity, or those with ED and urinary symptoms.

Tadalafil 10mg or 20mg tablets (on-demand use)

If you only want to take Tadalafil when you need it, an on-demand dose might be more suitable.

Instructions: Take one tablet 30-60 minutes before sexual activity.

10mg: Usually the recommended starting dose for occasional use. Take it 30–60 minutes before sexual activity.

20mg: A higher-strength option if 10 mg isn’t effective enough. It offers a more powerful response but also carries a higher chance of side effects.

Best for: occasional sexual activity or when you want a stronger effect.

Important: Never exceed one dose in 24 hours, and do not combine daily and on-demand treatments. Your clinician will help determine the most suitable dose based on your age, health, and treatment goals.

Tadalafil Side Effects

Like all prescription medicines, Tadalafil can cause side effects. Not everyone experiences them, and most are usually mild and short-lived. There are no known long-term side effects associated with Tadalafil.

Common Tadalafil side effects (affecting up to 10% of users)

These are the most frequently reported side effects and often improve as your body gets used to the medication:

  • Headache
  • Muscle pain
  • Flushing (warm, red skin)
  • Nasal congestion or a blocked nose
  • Indigestion (dyspepsia)

While rare, some side effects require immediate medical attention. Seek urgent medical attention if you experience:

  • A painful erection or one lasting more than 4 hours (priapism)
  • Sudden loss or changes to vision or hearing
  • Signs of a severe allergic reaction, including difficulty breathing, severe rash, or swelling of the lips, eyes, mouth, or throat

Read the patient information leaflet supplied with your medication for a full list of side effects.

Tadalafil Warnings

Although Tadalafil is generally suitable for most men with erectile dysfunction, this does not mean that everyone can take it. Please read the following warnings.

You should speak to your doctor about taking Tadalafil if you have:

  • Recently had a heart attack or stroke (within the last 3 months)
  • An eye condition called optic neuropathy
  • Low blood pressure
  • Heart failure
  • Been advised to avoid exercise or sexual activity
  • Abnormal heart rhythm, angina or high blood pressure that is not controlled
  • Deformation of the penis
  • A higher chance of a prolonged erection (e.g. if you have sickle-cell disease, multiple myeloma or leukaemia)
  • Stomach ulcers

Tadalafil Interactions

Tadalafil is generally safe to take with most medications. You should speak to your doctor before taking Tadalafil if you are taking:

  • Alpha blockers such as alfuzosin, doxazosin or tamsulosin
  • Medication to treat blood pressure
  • Any heart medication
  • Medication to treat epilepsy
  • Antifungal treatment
  • Crizotinib, enzalutamide, imatinib, nilotinib, idelalisib prescribed to treat some cancers
  • HIV medication
  • Erythromycin, clarithromycin, or rifampicin (antibiotics)
  • Netupitant or aprepitant prescribed to treat sickness
  • Nitrates
  • St John’s Wort
  • Sapropterin

If you are taking any of these medications, you may still be able to take Tadalafil, but your doctor may wish to monitor you, or you may need to leave a gap before taking a tablet.

FAQs

Yes, we use non-branded packaging with no mention of what is inside the parcel, or where it comes from.

Tadalafil lasts longer than sildenafil, however, both treatments vary in effectiveness on an individual basis.

To find out more, read our article: Tadalafil vs Sildenafil.

No. You should leave a 24-hour gap between both treatments.

Yes – you should use a pill cutter to do this.

Yes, however this is at the discretion of your doctor. Tadalafil is only prescribed on the NHS to those with certain medical conditions such as diabetes, cancer, Parkinson’s disease and multiple sclerosis.

No.

You can drink in moderation; however, excessive alcohol consumption can reduce the effectiveness of treatment.

Tadalafil 10mg can be purchased over the counter, after a consultation with a pharmacist. Tadalafil 2.5mg, 5mg and 20mg need a prescription.

Product Reviews

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"Fausto's Review"

Excelent product

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"Crawford's Review"

Seems to work well with no side effects.

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"Andrew's Review"

I have been using it for about 3 years and it has worked as described.

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"Michael's Review"

Does what it's supposed to do

By Michael Walsh (via Reviews.io)
Authored By
Abbas Kanani

Superintendent Pharmacist

Written by Chemist Click

First created 25th April 2025

Last reviewed 9th October 2025

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