Tadalafil Tablets
2.5mg / 5mg / 10mg / 20mg

Buy Tadalafil Online From a UK Pharmacy

You can buy tadalafil online in the following way:

1. Complete an online questionnaire
2. Choose your treatment option
3. Receive your order in plain and discrete packaging

You can order tadalafil tablets in the 2.5mg, 5mg, 10mg and 20mg strength. All orders are checked by a pharmacist to ensure that it is safe to prescribe tadalafil.  

What is tadalafil?

Tadalafil tablets are a medicine used to treat erectile dysfunction (ED).  They belongs to the class of drugs known as PDE-5 inhibitors. It has the same active ingredient as Cialis, but it is the generic (non-branded) version. It is often referred to as "generic Cialis". Tadalafil is available as two different variations.

Tadalafil 2.5mg & tadalafil 5mg - known as tadalafil daily
Tadalafil 10mg & tadalafil 20mg - known as tadalafil 36 hour

For more information on tadalafil, take a look at our in-depth guide that discusses ‘What Is Tadalafil?’.

Our tadalafil reviews page provides an insight into how other users find this treatment.

How does tadalafil work?

Tadalafil tablets work by increasing the flow of blood to the penis when a man is sexually stimulated. The increase in blood flow causes an erection, allowing males to achieve and maintain an erection. 

Simply taking tadalafil on its own is not enough to give you an erection, you need to be sexually aroused for it to work. Like other erectile dysfunction treatments, tadalafil works by preventing the action of a chemical in your body called phosphodiesterase type 5.
Doing this helps to relax and widen the blood vessels and improve the flow of blood to the penis. This helps you to get and keep an erection for sexual intercourse.  

The science behind this mechanism is in the name, “PDE5 inhibitor”. Erectile dysfunction is caused when an enzyme called PDE5 is present in the penis. PDE5 breaks down cGMP, a chemical which allows blood to enter the penis, causing an erection. When there is not enough cGMP, an erection cannot occur. Tadalafil blocks the action of PDE5, so that cGMP is not broken down, and can exert its effect to allow blood to enter the penis and cause an erection.

Tadalafil dosage

The recommended starting tadalafil dose is 10mg. You should take one tablet around 30 minutes before sex. You should try the tablet on 8 separate occasions, as it can take while to get used to. If you feel that you require a stronger dose, you should speak to your doctor or pharmacist about increasing the dose to 20mg.

If you wish to benefit from the advantages of taking tadalafil daily, you should start by taking tadalafil 2.5mg tablets. If you feel that you require a higher dose, you should speak to your doctor or pharmacist about increasing the dose to 5mg. Tadalafil daily has a continuous effect and avoids scheduling sexual activity for those that wish to have a spontaneous sex life.

Taking a higher dosage will not mean that your medication will have a quicker effect, so ensure that you are taking medication as prescribed  and be aware that a higher dosage can increase your chance of side effects.

Important: You should not take more than one tadalafil tablet within a 24-hour period. If you feel you require a stronger dose, you should discuss this with your doctor or pharmacist.

Tadalafil 2.5mg daily tablets

Tadalafil 2.5mg is the starting dose for those wishing to take tadalafil daily. The chances of experiencing side effects are lower with the 2.5mg strength. If you have not been successful after 8 separate attempts, you should speak to your doctor or pharmacist about increasing the strength to tadalafil 5mg tablets.

Tadalafil 5mg daily tablets

Tadalafil 5mg is the higher strength tablet, usually prescribed for those who have not experienced the desired effects with the 2.5mg tablets. Your doctor or pharmacist may wish to start you off using the 5mg tablets. This can depend on factors such as your BMI and age.

Tadalafil 10mg tablets

Tadalafil 10mg is the starting dose for those wishing to take tadalafil on a “when required” basis. The chances of experiencing side effects are lower with the 10mg strength, in comparison with 20mg. You should only look to increase the dose if you have been unsuccessful after 8 separate attempts. If the 10mg tablets are working well for you, a dose increase is not necessary. This will increase the chances of experiencing side effects, and there are no proven benefits that an erection will be of a better quality if you increase the dose without the need to.

Tadalafil 20mg tablets

Tadalafil 20mg tablets are the next step up from 10mg. Your doctor or pharmacist may prescribe you with the 20mg strength if you have had limited success with the 10mg tablets. If you have tried the 20mg strength on 8 separate occasions with limited success, you may wish to try an alternative ED tablet.

How do you take tadalafil?

Tadalafil is available in the form of a tablet. Take one tablet with water, before or after a meal (food does not affect the absorption of tadalafil).

If you are taking the 10mg or 20mg “when required” dose, take one tablet around 30 minutes before sexual activity.

If you are taking the 2.5mg or 5mg “daily” dose, take one tablet around the same time every day.

Important note: You should not take more than one tadalafil tablet within a 24-hour period. If you feel you require a stronger dose, you should discuss this with your doctor or pharmacist.

How long does tadalafil take to work?

Tadalafil tablets can take anywhere between 30 and 60 minutes to work. It is important to note that the effects of this medication can also last for up to 36 hours, which may increase your chances of experiencing side effects. You will not feel the effects of this medication unless you are sexually aroused.

Tadalafil 2.5mg and 5mg are to be taken every day, and the effects take around 3-5 days to kick in. After the first few days of dosing, tadalafil will provide a continuous effect.

How long does tadalafil last?

Tadalafil has a long duration of action and lasts for up to 36 hours. It is often referred to as “the weekend pill”. This is because you can take it on a Friday night, and it can still be effective until Sunday. It is possible for the effects to last slightly longer, or shorter.

Tadalafil 2.5mg and 5mg have an ongoing effect providing that you take a tablet every day.

Important: Tadalafil will not make you last longer by prolonging the time it takes to ejaculate, but it can allow you to maintain a firm erection for a longer period of time. 

What if tadalafil is not working for me?

If tadalafil does not work, you should give it another chance. It may be a good idea to try taking tadalafil a full hour before sexual activity, or on an empty stomach. UK guidelines suggest that you should try tadalafil on 8 separate occasions, before deciding whether it is effective for you or not.

Important note: ​Tadalafil is only effective where there is sexual arousal, and it may be worth trying to find ways to achieve this. If you find that tadalafil is still not working for you, try increasing the dose. If you are already taking the maximum dose, it may be worth trying a different treatment. The most important thing to remember is not to give up as there is always a solution. 

Is tadalafil safe?

Tadalafil is generally safe and well tolerated; however, it is not recommended for those with certain medical conditions, or those taking certain medication which may cause an interaction. You should check with your doctor or pharmacist to see if it is safe for you to take.

Who should not use tadalafil tablets?

You should speak to a doctor if you have:

• An allergy to tadalafil tablets or any of the ingredients contained in it
• Kidney or liver problems
• A history of heart problems or cardiovascular disease
• Very high or very low blood pressure
• Visual or eye disturbances not including poor eyesight
• Stomach ulcers
• A bleeding disorder
• An anatomical deformation of the penis

Can I take tadalafil tablets if I am taking other medication?

Tadalafil is generally safe to take with most medication. You should speak to your doctor before taking tadalafil if you are taking:

• Alpha blockers such as alfuzosin, doxazosin or tamsulosin
• Medication to treat blood pressure
• Any heart medication
• Medication to treat epilepsy
• Antifungal treatment
• Crizotinib, enzalutamide, imatinib, nilotinib, idelalisib used to treat some cancers
• HIV medication
• Erythromycin, clarithromycin or rifampicin (antibiotics)
• Netupitant or aprepitant used to treat sickness
• Nitrates 
• St John's Wort
• Sapropterin

If you are taking any of these medications, you may still be able to obtain tadalafil, but your doctor may wish to monitor you, or you may need to leave a gap before taking a tablet. 

Tadalafil and alcohol

Drinking alcohol when using tadalafil is not advised, as it can exacerbate side effects such as dizziness, headaches, and a drop in blood pressure. Alcohol is also a contributing factor to ED and can affect your ability to achieve and maintain an erection. However, small amounts of alcohol may be consumed safely.

Tadalafil vs Viagra

Both tadalafil and Viagra are oral drugs used to treat erectile dysfunction and are amongst two of the most popular forms of medication. The side effects of these two medicines are similar, including nausea, stuffy nose and dizziness. 

Tadalafil appears to be more popular amongst men in recent times. It has a quicker onset of action, longer lasting effect, and a milder side-effect profile, which makes it a more sought-after treatment. It is also available as a daily tablet for men looking for a continuous solution to ED, something that sildenafil (Viagra) does not offer. 

However, many men are happy with sildenafil, finding that it works well for them. Sildenafil is cheaper than tadalafil, making it a preferred option for some. 

Both tadalafil and sildenafil have been on the market for several years and they are both effective erectile dysfunction treatments. No two individuals are the same and what you find works best for you, may not necessarily be the case for others. Therefore, it is important to find what works best for you.

If you’re interested in researching Viagra in a bit more detail, take a look at our ‘How Viagra Works’ guide.

Tadalafil vs sildenafil

Both treatments are oral medication used to effectively treat erectile dysfunction. In comparison, sildenafil takes longer to work, and the effects generally last up to four hours. 

Tadalafil, on the other hand, has a quicker onset of action and a longer duration of action. The side effects of these two medicines are generally similar, with the main difference that sets them both apart is the speed at which they work and the length of time they last.

Unlike tadalafil, sildenafil cannot be taken with food, and it is advised that you take the medication on an empty stomach. Not doing so can delay the onset of action and reduce the amount of drug that is available in the blood stream.

Many people opt for tadalafil over sildenafil because of its quicker onset of action. However, because it has been established for longer, it has been suggested that there is a wider knowledge of the side effects and positive effects that sildenafil has in comparison to tadalafil.

For more information on the differences between the two, take a look at our guide ‘Sildenafil vs Tadalafil’.

Tadalafil vs Cialis

Tadalafil and Cialis are essentially the same medicine. Cialis is the brand name, whilst tadalafil is the generic name. They can vary slightly on appearance as different manufacturers produce them. Both have the same active ingredient, which is tadalafil. 

Cialis is the branded version that was introduced to the market by Eli Lily, a pharmaceutical company. 

They held a license, known as a patent, which gave them exclusive rights to be the sole producer of tadalafil, which they called Cialis. Since the patent has expired, other pharmaceutical manufacturers have been producing tadalafil at a cheaper price. They contain the same active ingredient and have the same clinical effectiveness.

Do tadalafil tablets lower blood pressure?

Tadalafil can lower blood pressure and you should not use it if you have low blood pressure. If you are taking medication to treat high blood pressure, tadalafil may cause your blood pressure to drop to a dangerously low level. You should check with your doctor or pharmacist to see if there is an interaction.

Is tadalafil legal?

In the UK, tadalafil is legal and can be obtained from a registered prescriber such as a doctor or a pharmacist independent prescriber.

Is tadalafil better than Viagra (sildenafil)?

Both tadalafil and sildenafil are similar in nature and belong to the same class of drugs, PDE-5 inhibitors. Tadalafil offers more advantages as it is available as a 2.5mg and 5mg tablet that can be taken daily to provide a continuous effect. The 10mg and 20mg tablets last for up to 36 hours, whereas sildenafil tablets last for up to 4 hours.  

Different people have different responses to treatment and tadalafil may be used where a person suffers from side effects from sildenafil and vice versa.

Can you get tadalafil on the NHS?

Tadalafil is available on the NHS if you have certain medical conditions such as diabetes. The limit is 4 tablets per month.

Does tadalafil work after ejaculation?

After ejaculation, it is likely that your penis will return to its flaccid state. After ejaculating, sexual stimulation normally decreases. Sexual excitement is still required for tadalafil to work; therefore, it is unlikely that an erection will be maintained after ejaculation.

Can tadalafil permanently cure ED?

Tadalafil works to help achieve and maintain an erection where there is sexual stimulation. It cannot cure erectile dysfunction permanently.  

Can women take tadalafil tablets?

Tadalafil is licensed to treat ED in males. Women can only use tadalafil if it is prescribed by a specialist to treat high blood pressure in the lungs.

Can you get tadalafil tablets over the counter in the UK?

Currently, in the UK, you cannot buy tadalafil over the counter. Viagra Connect and Eropid are the only licensed ED treatments available to buy over the counter without a prescription. 

At Chemist Click, we offer a range of effective erectile dysfunction treatments that are available to buy online through our website. Once a simple online consultation has been completed and approved by one of our medical professionals, we will ship you the medication in a discreet, plain package.

Additional Resources

For more information pertaining to erectile dysfunction, take a look at our blog section. Chemist Click have a host of information on erectile dysfunction and various treatment options:

• Erectile Dysfunction: Psychological Or Physical?
• How To Treat Erectile Dysfunction?