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Buy Alli Weight Loss

Alli is a weight loss medicine available to buy over the counter from our trusted UK pharmacy. Buy Alli capsules in 60mg dosage online today. Complete a simple online questionnaire and your order will be processed by a UK registered prescriber and dispatched on a next day delivery service.

Alli Prices

Name & Dosage x84 Capsules
(1 Month)
x168 Capsules
(2 Months)
x252 Capsules
(3 Months)
Alli 60mg Capsules
(2 Months)
£65.99
Alli 60mg Capsules
(3 Months)
£97.49
Alli 60mg Capsules
(1 Month)
£34.49

Summary for Alli

Medication Class Lipase inhibitor
Mechanism of action Inhibition of gastrointestinal lipase, an enzyme that breaks down dietary fats (triglycerides) in the intestines
Active ingredient Orlistat
Strength 60mg
Effective within Starts working immediately, but takes several weeks to months to see results
Dosage Instructions One tablet, three times a day
Manufacturer GlaxoSmithKline Consumer Healthcare (UK)
Use with alcohol Not recommended

Key Points

  • Clinically proven weight loss capsules
  • Targets fat in your digestive system
  • For every 2 kg (4 lb) you lose from dieting alone, Alli could help you lose up to 1 kg (2 lb) more
  • Taken three times a day

What is Alli Weight Loss?

Alli is a licensed weight loss aid for people who are overweight and have a body mass index (BMI) of 28 or above. It targets fat in your digestive system, stopping it from being absorbed by your body. It is designed to help you to lose more weight compared to dieting alone. The active ingredient in this medicine is orlistat 60mg.

Alli Weight Loss and Alcohol

There is no direct interaction between Alli and alcohol, however alcohol is high in calories and can worsen gastrointestinal side effects. This can be counterproductive and undermine your weight loss efforts therefore it’s best to limit or stop alcohol consumption whilst using this treatment.

Alli Weight Loss Alternatives

Alli vs Orlistat

  • Both medicines contain orlistat as the active ingredient and work by stopping the enzyme that breaks down fats in the digestive system
  • Orlistat capsules contain the prescription-strength 120 mg, recommended for people with a BMI of 30 or higher
  • Alli weight loss contains 60 mg and is available over the counter, recommended for adults with a BMI of 25 or higher
  • They both have similar side effects, however the higher dose may cause more pronounced side effects
  • Some studies have suggested that the higher dose orlistat can lead to greater weight loss over time

Alli Weight Loss Ingredients

Active ingredient: Orlistat 60 mg

Inactive ingredients: Capsule filling: microcrystalline cellulose (E460), sodium starch glycolate, povidone (E1201), sodium laurilsulfate, talc. Capsule shell: gelatin, indigo carmine (E132), titanium dioxide (E171), sodium laurilsulfate, sorbitan monolaurate, black ink (shellac, iron oxide black (E172), propylene glycol). Capsule band: gelatin, polysorbate 80, indigo carmine (E132).

Alli Dosage Instructions

How to Take Alli Capsules

Alli tablets are most effective when used alongside a reduced calorie and low-fat diet. For your body to get used to this medicine, pick the date you’d like to start and begin your diet a few days beforehand, keeping a food record for reference.

Swallow one capsule with water, three times a day at breakfast, lunch and dinner. You can take it just before, during or up to one hour after meals.

You must not take Alli if you miss a meal, or the meal contains no fat because it does not work without fat.

Alli capsules should not be taken more than three times a day and for no longer than six months.

Alli Weight Loss Side Effects

You should stop taking Alli immediately if you experience any of the side effects listed below. This could be a sign of a serious allergic reaction.

  • Severe breathing difficulties
  • Sweating
  • A rash
  • Itching
  • Face swelling
  • Fast heartbeat
  • Collapse

Inform your doctor urgently if you have any of the following serious side effects: 

  • Bleeding from your rectum
  • Diverticulitis (inflammation of the large intestine) which can cause lower stomach pain, typically on the left, possibly with fever and constipation
  • Pancreatitis (inflammation of the pancreas) which can cause severe abdominal pain sometimes moving towards the back, possibly with fever, feeling sick and vomiting
  • Skin blistering that may burst
  • Severe stomach pain caused by gallstones
  • Hepatitis (inflammation of the liver) which can cause yellowing skin and eyes, itching, dark coloured pee, stomach pain and pain in the liver, sometimes with loss of appetite
  • Oxalate nephropathy

Common side effects are typically caused by how Alli works. These diet-related side effects can be managed better by eating lower-fat meals. You should inform your doctor or pharmacist if any of the following side effects become severe or bothersome.

Very Common Side Effects (more than 1 in 10 people) 

  • Wind, with or without oily spotting
  • Bowel motions that happen suddenly
  • Fatty, oily or soft stools

Common Side Effects (up to 1 in 10 people)

  • Stomach pain
  • Unable to hold your feces or stool
  • Runny/liquid stools
  • Increase in frequency of bowel motions
  • Anxiety

Alli Weight Loss Warnings

Alli may not be suitable for everyone, or adjustments may need to be made in some cases. Do not take this medicine if: 

  • You’re allergic to orlistat or any of the other ingredients of this medicine
  • You’re pregnant or breast-feeding
  • You’re taking ciclosporin
  • You’re taking warfarin or other blood thinning medicines
  • You have the condition cholestasis
  • You have problems absorbing food (chronic malabsorption syndrome)

You should discuss taking Alli with your GP or pharmacist beforehand if:

  • You have diabetes
  • You have kidney disease

Alli Weight Loss Interactions

Alli capsules can affect how some medicines work. You should not use Alli if:

  • You’re taking Ciclosporin which is used after organ transplants, for severe rheumatoid arthritis and some severe skin conditions
  • Taking warfarin or other medicines used to thin the blood
  • Acarbose – anti-diabetic medicine used to treat type 2 diabetes mellitus

Vitamin levels absorbed by your body can be reduced whilst using this medicine therefore it is recommended that you take a multivitamin every day. It should contain vitamins A, D, E and K. Taking it just before bed, outside of when you take Alli, will help ensure proper absorption of the vitamins.

It’s important to disclose any medications you may be taking with your doctor before you use this treatment. Alli can impact the effectiveness of the following medicines:

  • The oral contraceptive pill – may be less effective in cases of severe diarrhoea
  • Amiodarone – used for heart rhythm issues
  • Thyroid medicine (levothyroxine)
  • Medicines for epilepsy
  • Medicines to treat HIV
  • Medicines for depression, anxiety or psychiatric disorders
  • Medicines for high blood pressure
  • Medicines for high cholesterol

Important note: Avoid taking Alli with a meal containing too much fat as this may increase your chance of getting diet-related treatment side effects.

Alli Weight Loss and Pregnancy/Breastfeeding

Alli is not recommended for women who are pregnant because of its potential to interfere with nutrient absorption. It works by blocking the absorption of fats which could potentially lead to a decreased absorption of fat-soluble vitamins crucial for both the mother and the developing fetus, such as vitamins A, D, E, and K. Studies on the use of Alli in pregnant women are also limited and therefore it is typically advised against use during pregnancy.

There is a lack of scientific research around the use of Alli whilst breastfeeding. Alli may interfere with the absorption of the vitamins which are critical for the baby’s growth and development, potentially affecting the quality of breast milk and baby’s health. There is also uncertainty surrounding the small amounts of the drug which could pass into breast milk and what effects that might have on the baby, therefore it is not typically recommended.

Frequently Asked Questions

The best weight loss pill is based on individual needs and preferences. The effectiveness and safety will vary depending on your health and weight loss goals. It’s important to choose a weight loss pill that has been scientifically studied for its effectiveness. There are several options for you to choose from:

Xenical 120 mg blocks the absorption of fat and is available on prescription. It contains the active ingredient orlistat.

Alli weight loss pills are available as a 60 mg lower dosage and can be bought over the counter

Orlistat is the generic version of both Alli and xenical and works best when used in conjunction with a low-calorie diet. You can find out more about orlistat results and what to expect on our blog.

Orlistat mainly works in the GI tract and only very small amounts (about 1%) of the drug are absorbed systemically so it has minimal impact on the rest of the body. It takes 1-2 hours for half of the small amount that enters the bloodstream to be eliminated. Most of the drug is excreted in the feces within 3-5 days.

Alli is clinically proven and was licensed in January 2009. It is available without a prescription under the supervision of a pharmacist. Alli is one of the few weight loss medications approved for use on the NHS for weight management. To see results, Alli should be used in combination with a reduced calorie, lower-fat diet. You should also try to be more physically active before you start taking the capsules because this is an important part of a weight loss programme.

Orlistat is considered safe when used as prescribed. Like with all medication, it does come with potential side effects and may not be suitable for everyone. It’s important to read the patient information leaflet and always take this medicine exactly as described or as your doctor or pharmacist has told you.

You can buy Alli weight loss capsules from Chemist Click, a regulated online UK pharmacy. We have a variety of prescription and non-prescription tablets for weight loss to choose from. After you complete a short questionnaire, our UK-based clinicians will assess suitability and dispatch your order using discreet packaging on a next day delivery service.

Product Review

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"Vicky's Review"

These tablets work very quickly when taken at initial onset of my cluster migraine. I find if I leave and take when full migraine they take longer.

By Vicky (via TrustPilot)
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"Kitty's Review"

When ever I have a horrid migraine start take one of these 50mg little miracles and starts to work with in 20-30 mins… highly recommend Sumatriptans as they actually work and are cheaper than the other brands 👍🏼

By Kitty (via TrustPilot)
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"Lisa's Review"

I have suffered with migraines on and off for years which I used to take regular medication for. They have recently increased again due to peri menopause. These sumatriptan tablets prevent me having to take bucket loads of pain killers when a migraine strikes and keeps the nausea at a distance. Highly recommended.

By Lisa Goulding (via TrustPilot)
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"Daniela's Review"

Helps with my occasional migraines. Wish I'd discovered them earlier. I usually take one the moment I suspect it coming. Sometimes I pair with ibuprofen , but it's usually very effective!

By Daniela Nicula (via TrustPilot)
Authored By
Abbas Kanani

Superintendent Pharmacist

Written by Chemist Click

First created 30th April 2025

Last reviewed 2nd October 2025

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