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Dymista Nasal Spray

From £22.49 See Prices

Dymista is a nasal spray that helps to relieve symptoms of hayfever & allergies. Dymista contains an antihistamine (Azelastine) which works to reduce symptoms brought about by allergies and also contains a steroid that helps to reduce inflamation (Fluticasone).

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  • UK registered service UK registered service
From £22.49
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Dymista PRICES

Medicine x1 Nasal Spray x2 Nasal Sprays x3 Nasal Sprays
Dymista 137mcg/50mcg Nasal Spray £22.49 £43.98 £62.40

About Dymista

Key points

  • Has dual action as it contains an antihistamine and a steroid
  • One spray to be used twice a day
  • Fast-acting


Buy Dymista nasal spray online

You can buy Dymista online after completing an online consultation. Dymista is a prescription nasal spray which you cannot buy over the counter, so a pharmacist will need to review your consultation. If it is safe to do so, we will dispatch your medication using an express courier, with next-day delivery options available.

What is Dymista nasal spray?

Dymista is a nasal spray which contains two ingredients:

  • Azelastine hydrochloride – an antihistamine
  • Fluticasone propionate – a corticosteroid


Azelastine works to reduce the production of histamine, the chemical which causes an immune response. Fluticasone works to reduce inflammation within the nasal passage.


What is Dymista used for?

Dymista is used to relieve symptoms of allergy such as:

  • A runny or blocked nose
  • Sneezing
  • Postnasal drip
  • Itchy or tickly nose


Dymista is predominantly used in those who have had limited success with an antihistamine and a nasal steroid.

It is effective at treating symptoms caused by pollen, mould, house mites, pets, or dust.


Is Dymista a steroid?

Dymista is a steroid based nasal spray. The ingredient, fluticasone propionate belongs to the class of medication known as corticosteroids.


How does Dymista nasal spray work?

Dymista has two main ingredients which work together to provide defense against allergy symptoms.

Azelastine is an antihistamine, which works by preventing the release of histamine (the chemical which causes an immune response to allergens such as pollen, dust, house mites and mould).

Fluticasone is a steroid which reduces inflammation in the nasal passage. This helps to relieve symptoms associated with hay fever and allergies.


How long does Dymista nasal spray take to work?

You may start to feel the effects of Dymista from 30 minutes after administration. However, it can take several days of consistent use to feel the full effects from treatment. If you suffer from seasonal allergies, you should start using Dymista a few weeks before the season.


How long does Dymista stay in your system?

Dymista stays in your system for up to 48 hours, with the effects starting to ware off after around 12 hours. To reduce the likelihood of experiencing symptoms, you should continue to use Dymista until the allergen is not present.

Dymista dosage intructions

You should use “One spray twice daily in each nostril”.

It is important to use Dymista spray regularly, to benefit from the full effects of treatment.

Dymista nasal spray ingredients

Active ingredients: Azelastine hydrochloride 1000mcg and Fluticasone propionate 365mcg.

Inactive ingredients: Carmellose, microcrystalline cellulose, disodium edetate, sodium, polysorbate 80, phenylethyl alcohol, benzalkonium chloride, glycerol and purified water.

Dymista side effects

Like all medicines, Dymista nasal spray may cause side effects. Not everyone experiences them. Side effects of Dymista include:

Very common: Affecting more than 10% of users

  • Nosebleeds


Common: Affecting up to 10% of users

  • Headache
  • Funny taste in the back of your throat or mouth (this is temporary and will go away after a short while).
  • Funny smell


Uncommon: Affecting up to 1% of users

  • Nasal irritation including a dry nose


Always inform your doctor or pharmacist if you experience side effects.

Stop using Dymista and seek urgent medical attention if you experience:

  • Swelling of the mouth, lips, face, tongue or throat
  • Difficulty breathing
  • Difficulty swallowing
  • Sudden severe skin rash

Dymista nasal spray warnings

Do not use Dymista nasal spray if you have an allergy to any of its ingredients.

Seek advice from your GP or pharmacist before using Dymista if:

  • You have recently had an operation on your nose
  • You have or have recently had an infection in your nose
  • You have tuberculosis or an untreated infection
  • You have a change in vision or a history of increased ocular pressure, glaucoma, or cataracts
  • You have had or have previously had any problems with your liver
  • You suffer from impaired adrenal function


Is Dymista safe to use long-term?

Dymista is generally considered to be a safe and well-tolerated drug with minimal absorption into your bloodstream. However, with long-term use, some of the drug may enter your bloodstream. This can affect the production of hormones in your body, affecting growth in children. In rare cases, it can also reduce bone density, increasing the risk of osteoporosis.

If you are using Dymista long-term, your GP may wish to monitor you.

Dymista and pregnancy

Most nasal spray are safe to use during pregnancy, however, you should consult your doctor or pharmacist before using Dymista if you are pregnant.

Dymista and breastfeeding

As a very small amount of Dymista enters the blood, it is usually safe to take when breastfeeding. However, you should speak to your doctor or pharmacist beforehand if you wish to use treatment whilst breastfeeding.

Dymista interactions

Dymista does not interact with many drugs, as very small amounts of Dymista enter the bloodstream. You should let your GP know if you are taking:

  • HIV medication such as ritonavir and cobicistat
  • Antifungal medication such as ketoconazole
  • Any other nasal sprays

Dymista nasal spray alternatives

Dymista is expensive as it is one of the only nasal sprays which contains a steroid, and an antihistamine. However, there are cheaper alternatives to Dymista.


Effective over the counter antihistamine tablets include cetirizine and loratadine.


  1. NHS UK. (n.d.). About Fluticasone Nasal Spray and Drops. Retrieved February 20, 2024, from

  2. electronic Medicines Compendium. (n.d.). Fluticasone Propionate 50 micrograms/actuation Nasal Spray: Summary of Product Characteristics (SmPC). Retrieved February 20, 2024, from

Dymista travels up your nose and small amounts can trickle down to your throat. This can cause a bitter and unpleasant taste. It should only lasts for a few minutes.

No, Dymista is not licensed to treat sinusitis or any other nasal infections.

A moderate amount of alcohol can be consumed whilst using Dymista. However, excess amounts of alcohol can cause dizziness.

No, Dymista is a prescription only medication. You can buy Dymista online from our UK registered pharmacy, by completing a short questionnaire.

Yes, Dymista is available on the NHS, however, this will be at the discretion of your GP. It is likely that you will be asked to try over the counter treatments first.

HOW TO USE Dymista Nasal Spray

Shake the bottle

Shake the bottle

Gently shake the bottle a few times in an up-down motion

Remove dust cap and prime

Remove dust cap and prime

Remove the dust cap and hold the bottle as shown with your index and middle finger on the collar of the nozzle and your thumb underneath. If you are using your nasal spray for the first time or after a few days without use, press down with your index and middle finger until a fine mist is produced.

Blow your nose

Blow your nose

Blow your nose using a clean towel or tissue to clear your airways

Administer spray

Administer spray

Hold the bottle as shown and using your other hand, place a finger on your nose to close one nostril. Put the nozzle into the other nostril as far as is comfortable. Tilt your head forward and keep the bottle upright. Start breathing in slowly through your nose and at the same time press down firmly on the collar of the bottle to release one spray.

Breathe out

Breathe out

Breathe out through your mouth. Repeat step 4 if you have been instructed to administer more than one spray in each nostril.

Administer spray in other nostril

Administer spray in other nostril

Repeat steps 4 and 5 to administer the correct number of sprays in the other nostril

Product Reviews For Dymista Nasal Spray

Summary For Dymista Nasal Spray

Medication class Nasal steroid and antihistamine
Mechanism of action Blocks the chemical which causes symptoms and reduces nasal inflammation
Active ingredient Azelastine hydrochloride and fluticasone propionate
Strength 137mcg/50mcg
Effective within 30 minutes
Dosage instructions One spray in each nostril, twice daily
Manufacturer Mylan
Use with alcohol No known interaction


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